8/24/2023 0 Comments Steroid antifungal cream![]() Ketoconazole 2% + clobetasol proprionate 0.05% + neomycin 0.5% (C) Ketoconazole 2% + clobetasol proprionate 0.05% + gentamycin 0.1% + tolnaftate 1% (B) Ketoconazole 2% + clobetasol proprionate 0.05% +gentamycin 0.1% (A) Terbinafine 2% + clobetasol proprionate 0.05%+ ciprofloxacin 1% + metronidazole 1% (G-H) Terbinafine 2% + clobetasol proprionate 0.05% + ofloxacin 0.75% + ornidazole 2% (A-F) Miconazole 2% + beclomethasone 0.025% + neomycin 0.5% (J-K)Ĭlotrimazole 1% + beclomethasone 0.025% + neomycin 0.5% (A-G)Ĭlotrimazole 1% + beclomethasone 0.025% + gentamycin 0.1% (H-J)Ĭlotrimazole 1% + betamethasone 0.05% + gentamycin 0.1% (K) Miconazole 2% + clobetasol proprionate 0.05% + gentamycin 0.1% (H-I) ![]() Miconazole 2% + clobetasol proprionate 0.05% + neomycin 0.5% (A-G) Topical FDCs of antifungal agenst with corticosteroids These formulations account for over half of the sales of all topical steroids in the Indian market. Some of these steroid-antifungal cocktails cost lesser than the pure antifungal creams, provide quick symptomatic relief, and are easily available over the counter which makes them popular. People stop their use as the itching and redness disappear and reuse as symptoms remerge. These steroid cocktails are often used by patients as self-medication, for symptomatic relief without supervision by a trained specialist. In India, FDC creams containing steroid, antifungal, and antibacterial cocktails are easily available over the counter. Recently, the prevalence of superficial dermatophytosis has seen an alarming rise and ranges from 36.6% to 78.4% in different regions of India, and the present situation has been described by some experts as the “Great Indian Epidemic of Superficial Dermatophytosis.” Indiscriminate use of fixed-drug combination (FDC) of corticosteroids with one or more antifungal and antibacterial agents has been cited as a major reason for the emergence of chronic, atypical, recurrent, recalcitrant, and treatment-resistant cases of superficial dermatophytosis in epidemic proportion. Using it on other skin conditions may make them worse.Superficial dermatophytosis, commonly known as ringworm or tinea, is a common fungal infection affecting over 20% of the population worldwide.
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